Is goldenseal safe to take?
Goldenseal might be safe for most adults when taken by mouth in the short term. There is not enough reliable information to know if goldenseal is safe for long-term use. Women who are pregnant or breastfeeding should not use goldenseal, and it should not be given to infants.
Which drugs should not be taken with goldenseal?
Given the convincing evidence that goldenseal inhibits CYP3A4, it is likely that goldenseal inhibits the metabolism of other CYP3A4 substrates such as alfuzosin, calcium channel blockers, carbamazepine, colchicine, ergot alkaloids, phosphodiesterase inhibitors, ranolazine, vinca alkaloids, and selected members of other …
What happens when you take goldenseal?
Goldenseal is also used for the common cold and other upper respiratory tract infections, as well as stuffy nose and hay fever. Some people use goldenseal for digestive disorders including stomach pain and swelling (gastritis), peptic ulcers, colitis, diarrhea, constipation, hemorrhoids, and intestinal gas.
Does goldenseal cleanse the liver?
Research suggests that goldenseal may reduce the activity of certain liver enzymes responsible for breaking down drugs. As such, this herbal supplement may slow the detox process rather than promote it ( 1 , 17 ).
Is goldenseal a natural antibiotic?
Today, goldenseal is sold to help with digestion, soothe an upset stomach, and to kill bacteria. It is considered a natural antibiotic and is often combined with echinacea and promoted as strengthening the immune system.
What are the side effects of goldenseal?
Common side effects of goldenseal include: Excitability. Hallucinations. Constipation….Side effects of goldenseal overdose (OD) include:
- Cardiac damage.
- Death.
- Depression.
- Low blood pressure (hypotension)
- Nausea/vomiting.
- Nervousness.
- Paralysis.
- Respiratory failure.