What is retinal dysplasia?
Retinal dysplasia is an abnormal development and differentiation of the retina that results in folds of the sensory retina. II. Severity of the retinal dysplasia varies from simple folds to geographic lesions and retinal detachment.
Does retinal dysplasia cause blindness?
Retinal detachment from severe dysplasia usually occurs within the first 6-9 months of life and leads to complete blindness. Occasionally, bleeding in the back of the eye or secondary glaucoma may occur with retinal detachment.
Is retinal dystrophy serious?
Retinal dystrophies are a heterogeneous group of hereditary diseases that cause progressive and severe loss of vision by altering the anatomy and/or function of the retina. There is currently no cure, but research is being carried out to find ways of treating it in the coming years with gene and cell therapies.
What is multifocal retinal dysplasia?
Multifocal retinal dysplasia (MRD) is a type of inherited eye condition. It is typified histologically by retinal folds and rosettes which, on ophthalmoscopic examination, appear as focal or multifocal linear streaks (retinal folds) and oval to round lesions (rosettes).
Is retinal dysplasia inherited?
There are various causes for retinal dysplasia, the most common cause being inherited. RD may also result from viral infections, and exposure to toxins. In some cases retinal folds may be seen in young puppies around 6 to 8 weeks of age.
How does retinal dysplasia occur?
Retinal dysplasia is an eye disease affecting the retina of animals and, less commonly, humans. It is usually a nonprogressive disease and can be caused by viral infections, drugs, vitamin A deficiency, or genetic defects. Retinal dysplasia is characterized by folds or rosettes (round clumps) of the retinal tissue.
Is there a treatment for retinal dystrophy?
There is currently no cure for RP, and no proven treatments are available to slow the progression of the disease.
What causes dog retinal detachment?
Retinal detachment of both eyes is most often caused by an underlying medical condition such as glaucoma, high blood pressure and/or hypothyroidism. Exposure to toxins may also result in the detachment of the retina.
What causes retinal dystrophy?
Most retinal dystrophies are genetic. This means they are caused by a mistake in a person’s genes and both eyes are likely to be affected. Often the gene mistake has been passed (inherited) from one or both parents. There are a number of different ways in which this can happen (see ‘Inheritance’ section).
Can you drive with Stargardt disease?
These low vision optics enable you to read signs and see traffic lights in the distance. So getting a driver’s license and driving safely with Stargardt disease – even if you are legally blind – can be an option!
What do you need to know about retinal dysplasia?
Retinal dysplasia is a congenital malformation of the retina, with the formation of folds or rosettes that appear clinically as retinal folds or larger areas of geographic dysplasia. Retinal dysplasia can be developmental or occur as a result of inflammation.
Can a dog have focal retinal dysplasia?
Most cases of retinal dysplasia in dogs are hereditary. It can involve one or both retinas. Retinal dysplasia can be focal, multifocal, geographic, or accompanied by retinal detachment. Focal and multifocal retinal dysplasia appears as streaks and dots in the central retina.
When does a springer spaniel develop retinal dysplasia?
The English Springer Spaniel inherits retinal dysplasia as an autosomal recessive trait. Lesions are bilateral, nonprogressive, and appear in the tapetal fundus as lightly colored round or linear lesions at 6 to 8 weeks of age, usually segregating along the retinal vasculature.
What is the difference between diffuse and multifocal retinal dysplasia?
In multifocal RD, vermiform streaks or spots are seen typically around the large retinal blood vessels superior to the optic disk. The lesions are most often bilateral but the extent of the retinal changes may vary between the eyes. In diffuse RD the eye is blind, while in multifocal RD vision is usually unaffected.