What are the types of stem cells present in the pulp?
The presence of different types of MSC populations in teeth has been described, which depending on the harvest site are called dental pulp stem cells (DPSCs), periodontal ligament stem cells (PDLSCs), apical papilla stem cells (SCAPs), dental follicle stem cells (DFSCs), and gingival tissue stem cells (GMSCs) [2].
Where are dental pulp stem cells found?
teeth
Dental Pulp Stem Cells (DPSCs): A New Source of Adult Stem Cells. The dental pulp is a soft tissue located in the center of teeth. It comprises blood vessels, neural fibers, and connective tissue. The dental pulp contains both mesenchymal and ectodermal tissue as well as neural crest cells (16).
Does dental pulp have stem cells?
The inner area of dental pulp chamber contains a highly proliferative stem/progenitor cells possessing a self-renewal and differentiation properties[17]. It has been shown that after teeth eruption, there is an induction of reparatitive dentin formation which protects dental pulp from further degradation[17].
What can dental pulp stem cells be used for?
DPSCs are able to differentiate into cells of the odontoblastic and osteoblastic lineage and have been reported to have the potential for use in cell-based therapy for systemic disease, such as neurological and cardiac diseases, and to ameliorate ischemic disease.
How is pulp formed?
The dental pulp develops from the neural crest cells in the fetus which condense to form the dental papilla. The mature pulp has a layer of highly specialized cells called odontoblasts that lie around the outer borders of the pulp. The dental pulp itself has a rich supply of blood vessels and nerves.
What is dental pulp?
Dental pulp is the center part of a tooth comprised of connective tissue, blood vessels, and cells. If this gets infected it may become painful and need root canal therapy to salvage the tooth. It is very important to have healthy pulp — please enjoy some fun dental pulp trivia!
Why are blood vessels found in the pulp cavity?
The blood vessels, nerves etc. of dental pulp enter and leave the tooth through this foramen. This sets up a form of communication between the pulp and surrounding tissue – clinically important in the spread of inflammation from the pulp out into the surrounding periodontium.
What are the zones of pulp?
The pulp cavity exhibits four zones as you progress from the dentin-pulp junction toward the center of the pulp cavity: 1) the odontoblast zone, 2) cell-free zone (basal layer of Weil), 3) cell-rich zone, and 4) the pulp core.
What is the pulp in your teeth?
What is normal dental pulp?
The pulp is the neurovascular bundle central to each tooth, permanent or primary. It comprises a central pulp chamber, pulp horns, and radicular canals. The large mass of pulp is contained within the pulp chamber, which is contained in and mimics the overall shape of the crown of the tooth.
Do you know the 5 types of dental stem cells?
Do You Know The 5 Types of Dental Stem Cells? Dental Pulp Stem Cells (DPSCs) Dental Follicle Progenitor Cells (DFPCs) Stem Cells from Apical Papilla (SCAP) Periodontal Ligament Stem Cells (PDLSCs) Stem Cells from Human Exfoliated Deciduous Teeth (SHED)
Is there collagen in dental pulp?
The main macromolecules in the dental pulp are collagenous proteins (especially types I and III collagen), non-collagenous proteins (fibronectin, tenascin, osteonectin, sialoprotein and osteocalcin) and proteoglycans, including hyaluronic acid, chondroitin sulphate, heparin sulphate and phospholipids. 2, 3, 5, 6.
What is dental stem cell?
Dental pulp stem cells. Dental pulp stem cells (DPSCs) are stem cells present in the dental pulp, which is the soft living tissue within teeth.
What is dental stem cell banking?
Tooth Banking is the storing of dental stem cells that have the ability to regenerate into various cell types. When your child’s tooth or your own is extracted by a dental professional, dental stem cells are harvested from the dental pulp within the tooth.