Where is the synovial membrane located?
joints
A layer of connective tissue that lines the cavities of joints, tendon sheaths, and bursae (fluid-filled sacs between tendons and bones).
What will happen if the synovial membrane damage?
When any part of the synovial joint becomes damaged, it can cause parts of the joint to wear down, leading to pain and limited mobility. The most common cause of synovial joint pain is overuse.
What does the synovial membrane do in the knee?
The synovial membrane of the knee is the inner aspect of the knee capsule, which produces synovial fluid to aid in the lubrication of the knee joint. It is also reflected on to the articular margins of the femur, tibia and patella.
How do you treat a synovial membrane?
Treatment for synovitis usually consists of rest and anti-inflammatory medications. Medications may include oral drugs known as DMARDs (disease-modifying antirheumatic drugs) and, in some cases, steroid injections.
What fluid is produced in the synovial membrane?
Synovial fluid (SF) is the viscous liquid in the synovial cavity and is secreted by the synovial membrane.
Is bursitis the same as synovitis?
Bursitis is inflammation of a bursa: a small, jelly-like sac located throughout the body, including around the shoulder, elbow, hip, knee, and heel. Repeated small stresses and overuse can cause a bursa in the shoulder, elbow, hip, knee, or ankle to swell. Synovitis is the inflammation of the synovial membrane.
What makes the synovial membrane different?
It is the lack of epithelial cells within the initma which defines the synovial membrane as connective rather than epithelial. The type B synoviocytes manufacture a long-chain sugar polymer called hyaluronan, which makes the synovial fluid together with a molecule called lubricin, which lubricates the joint surfaces.
How are synovial cells related to the fibrous membrane?
It makes direct contact with the fibrous membrane on the outside surface and with the synovial fluid lubricant on the inside surface. In contact with the synovial fluid at the tissue surface are many rounded macrophage -like synovial cells (type A) and also type B cells, which are also known as fibroblast-like synoviocytes (FLS).
What makes up the surface of the synovial fluid?
The synovial fluid is composed mainly of hyaluronic acid, glycoproteins and transudate capillaries within the synovial membrane. The synovial membrane is composed of adipose and fibrous tissue, they have a smooth non-adherent surface that allows easy movement between tissues. The surface is permeable to proteins, water and small molecules.
Are there any inflammatory mediators in the synovial membrane?
The synovial membrane is well-vascularized and innervated, and activated synoviocytes release a range of inflammatory mediators, including kinins, leukotrienes, prostaglandins, and acute-phase proteins like serum amyloid A.
Which is part of the synovial membrane makes the egg white?
The fibroblastic synovial cells (derived from mesenchyme) manufacture a long-chain sugar polymer called hyaluronan (hence rich in endoplasmic reticulum ); which makes the synovial fluid “ropy”-like egg-white, together with a molecule called lubricin, which lubricates the joint surfaces.